更新時(shí)間:2016-06-13
放線菌素 D,關(guān)于產(chǎn)品的Cas號(hào)、分子式、分子量、性狀、熔點(diǎn)等化學(xué)及物理性質(zhì),貯存、用途等具體信息,可向我們生化試劑專業(yè)銷售人員索取,紙質(zhì)說明書,我們隨貨發(fā)出。
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放線菌素 D
Actinomycin D
Cas 號(hào): 50-76-0 M D L:
放線菌素 D 分子式: C62 H86 N12 O16 分子量: 1255.44
別 名: 更生霉素D;硫化劑雙-25;
更生霉素,DACTINOMYCIN
1MG
性 狀: 熔點(diǎn) 251-253 °C
溶解度 ethanol, DMSO: Stable in aqueous solutions at 2-8 °C.soluble
form powder
color red, powder
水溶解性 SOLUBLE
質(zhì)量標(biāo)準(zhǔn): 鮮紅色結(jié)晶性粉末,有吸濕性,光照下漸失去活性。比旋光度[α]18D-315°(0.02%,甲醇)。不溶于石油醚,微溶于水,溶于甲醇、乙醇及乙酸乙酯,易溶于苯、氯仿和丙酮。LD50(大鼠,經(jīng)口)7200 μg/kg。
貯 存: 儲(chǔ)存條件 2-8°C
用途 干擾素誘導(dǎo)劑,臨床用于抗腫瘤藥物。
該品對(duì)惡性葡萄胎療效較顯著,對(duì)腎母細(xì)胞瘤、何杰金氏病、睪丸腫瘤、橫紋肌肉瘤、神經(jīng)母細(xì)胞瘤和網(wǎng)狀細(xì)胞肉瘤有效。以宮頸癌、卵巢癌、乳腺癌和消化道癌等,也有一定的療效。與放療聯(lián)合應(yīng)用可提高放療的敏感性。
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